Department of Clinical Genetics


RNDr. Regína Lohajová Behulová, PhD. (regina.behulova[at]

Head of the Department

Katarina Zavodna

RNDr. Katarína Závodná, PhD. (katarina.zavodna[at]

Deputy Chief

Olivia Hamidova

Olívia Hamidová, M.D. (olivia.hamidova[at]

Clinical Geneticist

Ludmila Vavrova

Ing. Ľudmila Vavrová, PhD. (lvavrova[at]

Tomas Slamka

Mgr. Tomáš Slamka (tomas.slamka[at]

Lenka Dolesova

Mgr. Lenka Dolešová (lenka.dolesova[at]

Aster Alemayehu

RNDr. Aster Alemayehu, PhD.(aster.alemayehu[at]

Aster Alemayehu

Mgr. Daniela Žideková (daniela.zidekova[at]

Aster Alemayehu

Mgr. Lukáš Šebest (lukas.sebest[at]

Laboratory Technicians:

Jana Štohlová (jana.stohlova[at]

Iveta Glozneková

Mgr. Jaroslava Gregorová

Beatrix Jánošová

Ružena Kozlová

Mgr. Žofia Svoreňová

Jana Némethová

Available Tests

Hereditary syndromes:

Hereditary Breast and Ovarian Cancer (HBOC; BRCA1 and BRCA2 genes)

Hereditary Breast and Ovarian Cancer (HBOC), Li-Fraumeni syndrome, familial prostate cancer (CHEK2 gene)

Hereditary form of medullary carcinoma (MEN 2; RET gene)

Hereditary malignant melanoma (HMM; CDKN2A gene)

Testing of microsatellite instability in colorectal tumors (MSI)

Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome; MLH1, MSH2, MSH6 genes, detection of large genomic rearrangements)

Hereditary diffuse gastric cancer (HDGC; CDH1 gene)

Hereditary chronic pancreatitis (HCP; PRSS1 and SPINK1 genes)

Hereditary angioedema (HAE; SERPING1 gene)


Somatic mutations in sporadic tumors:

Analysis of somatic mutations in KRAS/NRAS genes in metastatic colorectal cancer (codons 12, 13, 59, 61, 117, 146)

Analysis of somatic mutations in BRAF gene in papillary thyroid tumors & melanomas (codon 600)

Analysis of somatic mutations in EGFR gene in non-small cell lung carcinoma (exons 18-21)

Analysis of ALK gene rearrangements in non-small cell lung carcinoma

Prediction test of severe and lethal toxicity of fluoropyrimidines (DPYD analysis)


Analysis of diagnostic markers

Non-invasive screening of colorectal cancer from peripheral blood – analysis of Septin9 gene methylation

Diagnosis of lung cancer – analysis of SHOX2 gene methylation

Analysis of IDH1 (codon 132) and IDH2 genes (codon 172) in patients with glioblastomas


Analysis of human papillomaviruses (HPV) and Chlamydia/Neisseria infections

High-risk HPV testing (Cobas® 4800 HPV Test)

Testing and genotyping of high/low-risk HPV viruses

Identification of malignant precursors by testing for expression of E6/E7 HR-HPV oncogenes

Analysis of methylation of genes associated with cancer progression (PreCursor-M test; CADM1, MAL, miR124-2 genes)

Analysis of Chlamydia trachomatis and Neisseria gonorrhoeae infections




EMQN 2015

NGS 2015

RAS 2014


HPV 2012

KRAS 2012


KRAS 2011

KRAS 2010

EMQN 2011

EMQN 2010

EMQN 2009

EMQN 2008

HPV 2015

HPV 2016
EMQN 2015 autumn